MSM vs. Methylsulfonylmethane

What's the Difference?

MSM (Methylsulfonylmethane) and Methylsulfonylmethane are actually the same compound, with MSM being the commonly used abbreviation. It is an organic sulfur compound that is naturally found in plants, animals, and humans. MSM is often used as a dietary supplement to support joint health, reduce inflammation, and improve skin conditions. It is also known for its potential antioxidant and anti-inflammatory properties. Overall, MSM and Methylsulfonylmethane refer to the same beneficial compound that is widely used for its potential health benefits.


Chemical FormulaC2H6O2SC2H6O2S
Full NameMethylsulfonylmethaneMethylsulfonylmethane
Common AbbreviationMSMMSM
AppearanceWhite crystalline powderWhite crystalline powder
SolubilityHighly soluble in waterHighly soluble in water
UsesSupplement for joint health, skin, and hairSupplement for joint health, skin, and hair
SourceNaturally found in plants and animalsNaturally found in plants and animals
Medical BenefitsReduces inflammation, relieves arthritis symptomsReduces inflammation, relieves arthritis symptoms

Further Detail


MSM, also known as Methylsulfonylmethane, is a naturally occurring compound found in various foods and used as a dietary supplement. It is a sulfur-containing compound that has gained popularity for its potential health benefits. In this article, we will explore the attributes of MSM and its potential effects on the body.

Origin and Composition

MSM, or Methylsulfonylmethane, is an organic sulfur compound that can be found in various plant and animal tissues. It is formed through the oxidation of dimethyl sulfide, a compound found in seaweed and other marine organisms. MSM is composed of carbon, hydrogen, oxygen, and sulfur atoms, with the chemical formula (CH3)2SO2.

On the other hand, Methylsulfonylmethane is the full name for the compound commonly referred to as MSM. It is often used interchangeably with the acronym MSM, which stands for Methylsulfonylmethane. Both terms refer to the same compound and can be used synonymously throughout this article.

Health Benefits

MSM has been studied for its potential health benefits and is commonly used as a dietary supplement. Some of the reported benefits of MSM include:

  • Joint Health: MSM is believed to support joint health by reducing inflammation and improving joint flexibility. It may also help alleviate symptoms of arthritis and joint pain.
  • Skin Health: MSM is often used in skincare products due to its potential benefits for the skin. It may help improve skin elasticity, reduce wrinkles, and promote a more youthful appearance.
  • Exercise Recovery: Some studies suggest that MSM may aid in exercise recovery by reducing muscle damage and inflammation. It may also help alleviate muscle soreness and improve overall exercise performance.
  • Allergy Relief: MSM has been investigated for its potential to reduce allergy symptoms, such as sneezing, itching, and congestion. It may help modulate the immune response and reduce the release of inflammatory substances.
  • Antioxidant Properties: MSM is believed to possess antioxidant properties, which can help protect cells from oxidative stress and damage caused by free radicals.

Availability and Dosage

MSM is available as a dietary supplement in various forms, including capsules, tablets, powders, and creams. It can be found in health food stores, pharmacies, and online retailers. The recommended dosage of MSM varies depending on the specific health condition and individual needs. However, a typical dosage ranges from 1,000 to 6,000 milligrams per day, divided into multiple doses.

It is important to note that while MSM is generally considered safe for most people, it is always advisable to consult with a healthcare professional before starting any new supplement regimen. They can provide personalized recommendations based on your specific health needs and potential interactions with other medications or conditions.

Potential Side Effects

MSM is generally well-tolerated, and side effects are rare. However, some individuals may experience mild gastrointestinal symptoms, such as bloating, diarrhea, or nausea, when taking higher doses of MSM. If any adverse reactions occur, it is recommended to reduce the dosage or discontinue use.

It is worth mentioning that MSM is not recommended for individuals with a known allergy or sensitivity to sulfur compounds. Additionally, pregnant or breastfeeding women should consult with their healthcare provider before using MSM as a dietary supplement.


MSM, or Methylsulfonylmethane, is a naturally occurring compound that has gained popularity as a dietary supplement. It offers potential benefits for joint health, skin health, exercise recovery, allergy relief, and possesses antioxidant properties. MSM is available in various forms and dosages, but it is important to consult with a healthcare professional before starting any new supplement regimen. While side effects are rare, individuals with sulfur allergies or sensitivities should avoid MSM. Overall, MSM shows promise as a natural compound with various potential health benefits.

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