Metoprolol vs. Metoprolol Succinate

Attribute	Metoprolol	Metoprolol Succinate
Drug Class	Beta blocker	Beta blocker
Brand Name	Lopressor	Toprol XL
Dosage Forms	Tablet, Injection	Extended-release tablet
Half-life	3-7 hours	3-7 hours
Indications	Hypertension, Angina, Heart failure	Hypertension, Angina, Heart failure

Introduction

Metoprolol and Metoprolol Succinate are both medications that belong to a class of drugs known as beta-blockers. They are commonly prescribed to treat high blood pressure, chest pain (angina), and heart failure. While both medications have similar uses, there are some key differences between the two that patients should be aware of.

Metoprolol

Metoprolol is the generic name for a medication that is also sold under brand names such as Lopressor and Toprol XL. It is typically used to treat high blood pressure and angina. Metoprolol works by blocking the action of certain natural chemicals in the body, such as epinephrine, on the heart and blood vessels. This helps to lower blood pressure, reduce chest pain, and improve overall heart function.

• Used to treat high blood pressure and angina
• Blocks the action of certain natural chemicals in the body
• Available under brand names Lopressor and Toprol XL

Metoprolol Succinate

Metoprolol Succinate is a specific formulation of Metoprolol that is designed to be taken once daily. It is commonly prescribed for the treatment of high blood pressure and heart failure. Metoprolol Succinate works in a similar way to Metoprolol by blocking the effects of certain natural chemicals in the body. However, the extended-release formulation allows for a longer duration of action, making it more convenient for patients who only need to take one pill per day.

• Formulation designed for once-daily dosing
• Used to treat high blood pressure and heart failure
• Extended-release formulation for longer duration of action

Key Differences

One of the main differences between Metoprolol and Metoprolol Succinate is the dosing schedule. Metoprolol is typically taken multiple times per day, while Metoprolol Succinate is taken once daily. This can be a significant factor for patients who prefer the convenience of a once-daily medication. Additionally, the extended-release formulation of Metoprolol Succinate allows for a more consistent level of the medication in the body over time.

Another key difference is the specific conditions that each medication is commonly used to treat. While both Metoprolol and Metoprolol Succinate are used to treat high blood pressure, Metoprolol Succinate is also commonly prescribed for heart failure. This may influence a healthcare provider's decision when choosing which medication to prescribe for a particular patient.

Similarities

Despite their differences, Metoprolol and Metoprolol Succinate also have several similarities. Both medications work by blocking the effects of certain natural chemicals in the body, specifically epinephrine, on the heart and blood vessels. This helps to lower blood pressure, reduce chest pain, and improve overall heart function. Additionally, both medications are generally well-tolerated by most patients when taken as directed.

Another similarity is that both Metoprolol and Metoprolol Succinate can cause side effects such as dizziness, fatigue, and low blood pressure. Patients should be aware of these potential side effects and discuss any concerns with their healthcare provider. It is important to follow the prescribed dosing schedule and not to stop taking the medication without consulting a healthcare professional.

Conclusion

In conclusion, Metoprolol and Metoprolol Succinate are both effective medications for the treatment of high blood pressure, chest pain, and heart failure. While they have similar mechanisms of action, there are key differences in their dosing schedules and specific uses. Patients should work closely with their healthcare provider to determine which medication is best suited to their individual needs and medical history.