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Ferric Ammonium Citrate vs. Ferrous Ascorbate

What's the Difference?

Ferric Ammonium Citrate and Ferrous Ascorbate are both iron supplements commonly used to treat iron deficiency anemia. However, they differ in their chemical composition and absorption rates. Ferric Ammonium Citrate contains ferric iron, which is less readily absorbed by the body compared to ferrous iron found in Ferrous Ascorbate. Ferrous Ascorbate is a combination of ferrous iron and ascorbic acid, which helps enhance iron absorption. Overall, Ferrous Ascorbate is often preferred over Ferric Ammonium Citrate due to its higher bioavailability and effectiveness in treating iron deficiency.

Comparison

AttributeFerric Ammonium CitrateFerrous Ascorbate
Chemical FormulaC6H8O7Fe(NH4)3C18H16FeK3O14
Iron ContentFerric ironFerrous iron
ColorGreenPale yellow
UsageUsed in pharmaceuticals and as a food additiveUsed as a dietary supplement

Further Detail

Introduction

Iron is an essential mineral that plays a crucial role in various bodily functions, including the production of red blood cells and the transportation of oxygen. Ferric Ammonium Citrate and Ferrous Ascorbate are two common forms of iron supplements that are used to treat iron deficiency anemia. While both supplements provide the body with iron, they have distinct attributes that set them apart. In this article, we will compare the attributes of Ferric Ammonium Citrate and Ferrous Ascorbate to help you understand which one may be more suitable for your needs.

Chemical Composition

Ferric Ammonium Citrate is a complex salt that contains iron in the ferric form, which means that each molecule of iron is bound to three molecules of citric acid. On the other hand, Ferrous Ascorbate is a combination of iron in the ferrous form and ascorbic acid (vitamin C). The presence of ascorbic acid in Ferrous Ascorbate helps in the absorption of iron by the body, making it a more bioavailable form of iron compared to Ferric Ammonium Citrate.

Iron Content

When it comes to the iron content, Ferric Ammonium Citrate typically contains around 20% elemental iron, while Ferrous Ascorbate contains around 30% elemental iron. This means that Ferrous Ascorbate provides a higher concentration of iron per dose compared to Ferric Ammonium Citrate. However, the bioavailability of iron in Ferrous Ascorbate may vary depending on individual factors such as the presence of other nutrients in the diet.

Side Effects

Both Ferric Ammonium Citrate and Ferrous Ascorbate may cause side effects such as constipation, nausea, and stomach upset. However, some individuals may experience fewer side effects with Ferrous Ascorbate due to its better absorption rate. It is important to consult with a healthcare provider before starting any iron supplement to determine the appropriate dosage and monitor for any adverse reactions.

Indications

Ferric Ammonium Citrate is commonly used to treat iron deficiency anemia in individuals who are unable to tolerate other forms of iron supplements. On the other hand, Ferrous Ascorbate is often recommended for pregnant women and individuals with low iron levels due to its higher bioavailability. The choice between Ferric Ammonium Citrate and Ferrous Ascorbate may depend on the specific needs of the individual and their ability to absorb iron effectively.

Cost

In terms of cost, Ferric Ammonium Citrate is generally more affordable compared to Ferrous Ascorbate. This may be a consideration for individuals who need to take iron supplements on a long-term basis or those who are on a tight budget. However, the cost difference between the two supplements may vary depending on the brand and dosage strength.

Conclusion

Both Ferric Ammonium Citrate and Ferrous Ascorbate are effective forms of iron supplements that can help treat iron deficiency anemia. While Ferric Ammonium Citrate may be more cost-effective, Ferrous Ascorbate offers higher bioavailability and may be better tolerated by some individuals. Ultimately, the choice between the two supplements should be based on individual needs, preferences, and healthcare provider recommendations. It is important to follow the recommended dosage and monitor for any side effects when taking iron supplements to ensure optimal health outcomes.

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