Breztri vs. Dulera
What's the Difference?
Breztri and Dulera are both medications used to treat asthma and chronic obstructive pulmonary disease (COPD). Breztri is a combination medication containing three active ingredients - budesonide, glycopyrrolate, and formoterol fumarate - while Dulera contains two active ingredients - mometasone and formoterol. Both medications work by reducing inflammation and opening up the airways to improve breathing. However, Breztri is a newer medication and may be more effective for some patients with severe asthma or COPD. Dulera is also effective but may be more suitable for patients who have milder symptoms or are looking for a more established treatment option. Ultimately, the choice between Breztri and Dulera will depend on the individual patient's needs and preferences.
Comparison
| Attribute | Breztri | Dulera |
|---|---|---|
| Manufacturer | AstraZeneca | Merck |
| Generic Name | Budesonide, Glycopyrrolate, and Formoterol fumarate | Mometasone and Formoterol |
| Indication | Treatment of COPD | Treatment of asthma |
| Formulation | Inhalation powder | Inhalation aerosol |
Further Detail
Introduction
When it comes to managing respiratory conditions such as chronic obstructive pulmonary disease (COPD) and asthma, there are a variety of medications available on the market. Two commonly prescribed medications for these conditions are Breztri and Dulera. Both medications are used to help control symptoms and improve lung function in patients with these respiratory conditions. In this article, we will compare the attributes of Breztri and Dulera to help patients and healthcare providers make informed decisions about which medication may be best for their needs.
Active Ingredients
Breztri is a fixed-dose combination medication that contains three active ingredients: budesonide, glycopyrrolate, and formoterol fumarate. Budesonide is a corticosteroid that helps reduce inflammation in the airways, glycopyrrolate is a long-acting muscarinic antagonist that helps relax the muscles around the airways, and formoterol fumarate is a long-acting beta agonist that helps open up the airways. On the other hand, Dulera contains two active ingredients: mometasone furoate, a corticosteroid, and formoterol fumarate, a long-acting beta agonist. Both medications work to reduce inflammation and improve airflow in the lungs, but Breztri has an additional ingredient that helps relax the muscles around the airways.
Indications
Breztri is indicated for the maintenance treatment of COPD, including chronic bronchitis and emphysema. It is also approved for the treatment of asthma in patients who require a combination of an inhaled corticosteroid and a long-acting beta agonist. On the other hand, Dulera is indicated for the treatment of asthma in patients aged 12 years and older. It is not approved for the treatment of COPD. Patients should consult with their healthcare provider to determine which medication is most appropriate for their specific condition.
Dosage Forms
Breztri is available as an inhalation aerosol that is administered using a metered-dose inhaler. It is typically taken twice daily, with each dose containing a fixed combination of the three active ingredients. Dulera is also available as an inhalation aerosol that is administered using a metered-dose inhaler. It is taken twice daily, with each dose containing a fixed combination of mometasone furoate and formoterol fumarate. Both medications should be used regularly to achieve the best results.
Side Effects
Common side effects of Breztri may include headache, back pain, cough, and sore throat. Less common but more serious side effects may include pneumonia, thrush in the mouth and throat, and increased risk of bone fractures. Dulera may cause side effects such as headache, throat irritation, and sinusitis. It may also increase the risk of pneumonia and osteoporosis. Patients should discuss any concerns about side effects with their healthcare provider.
Cost
When it comes to cost, Breztri and Dulera may vary in price depending on factors such as insurance coverage and pharmacy discounts. Both medications are available in generic forms, which may be more affordable for some patients. Patients should check with their insurance provider and local pharmacies to compare prices and determine the most cost-effective option for their medication needs.
Conclusion
In conclusion, Breztri and Dulera are both effective medications for managing respiratory conditions such as COPD and asthma. Breztri contains three active ingredients that work together to reduce inflammation and improve airflow in the lungs, while Dulera contains two active ingredients with similar effects. Patients should work closely with their healthcare provider to determine which medication is best suited for their individual needs based on factors such as indications, dosage forms, side effects, and cost. By understanding the attributes of Breztri and Dulera, patients can make informed decisions about their respiratory health and overall well-being.
Comparisons may contain inaccurate information about people, places, or facts. Please report any issues.