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1,2-Hexanediol vs. Ethoxydiglycol

What's the Difference?

1,2-Hexanediol and Ethoxydiglycol are both commonly used in skincare and cosmetic products as humectants and solvents. However, they have different chemical structures and properties. 1,2-Hexanediol is a diol compound with six carbon atoms, while Ethoxydiglycol is a diethylene glycol monoethyl ether. 1,2-Hexanediol is known for its moisturizing and conditioning properties, while Ethoxydiglycol is often used as a solvent to enhance the penetration of other ingredients into the skin. Both ingredients are considered safe for use in cosmetics and are effective in improving the texture and hydration of the skin.

Comparison

Attribute1,2-HexanediolEthoxydiglycol
Chemical FormulaC6H14O2C8H18O4
Molecular Weight118.17 g/mol178.23 g/mol
AppearanceClear, colorless liquidClear, colorless liquid
OdorMild, characteristic odorOdorless
SolubilitySoluble in waterSoluble in water

Further Detail

Chemical Structure

1,2-Hexanediol is a colorless liquid with the chemical formula C6H14O2. It is a diol, meaning it has two hydroxyl groups attached to adjacent carbon atoms. On the other hand, Ethoxydiglycol, also known as diethylene glycol monoethyl ether, has the chemical formula C6H14O3. It is an ether compound with a hydroxyl group and an ethoxy group attached to the same carbon atom.

Physical Properties

1,2-Hexanediol has a boiling point of 250°C and a melting point of -50°C. It is soluble in water and has a mild, pleasant odor. Ethoxydiglycol, on the other hand, has a boiling point of 248°C and a melting point of -45°C. It is also soluble in water and has a slightly sweet odor.

Uses

1,2-Hexanediol is commonly used as a humectant in skincare products due to its ability to attract and retain moisture. It is also used as a solvent in various formulations. Ethoxydiglycol is often used as a solvent in cosmetics and personal care products. It helps to improve the stability and texture of formulations.

Safety

1,2-Hexanediol is considered to be a safe ingredient in skincare products when used in appropriate concentrations. It has low toxicity and is not known to cause skin irritation or sensitization. Ethoxydiglycol is also considered to be safe for use in cosmetics, with low potential for skin irritation or sensitization.

Stability

1,2-Hexanediol is stable under normal conditions and does not degrade easily. It is compatible with a wide range of other ingredients commonly used in skincare formulations. Ethoxydiglycol is also stable and compatible with many other ingredients, making it a versatile solvent for cosmetic products.

Regulatory Status

Both 1,2-Hexanediol and Ethoxydiglycol are approved for use in cosmetics and personal care products by regulatory agencies such as the FDA and the European Commission. They are considered safe for use in formulations at specified concentrations.

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