1,2-Hexanediol vs. 1-Methylhydantoin-2-Imide

Attribute	1,2-Hexanediol	1-Methylhydantoin-2-Imide
Molecular Formula	C6H14O2	C5H8N2O2
Molecular Weight	118.17 g/mol	128.13 g/mol
Chemical Structure	HO(CH2)6OH	CH3C(O)NHC(NH)NH
Physical State	Liquid	Solid
Boiling Point	250°C	Unknown

Chemical Structure

1,2-Hexanediol is a diol compound with the chemical formula C6H14O2. It consists of a six-carbon chain with hydroxyl groups attached to the second and third carbon atoms. On the other hand, 1-Methylhydantoin-2-Imide has a more complex structure with a hydantoin ring and a methyl group attached to one of the nitrogen atoms. The chemical formula for 1-Methylhydantoin-2-Imide is C5H6N2O2.

Physical Properties

1,2-Hexanediol is a colorless liquid with a mild odor. It has a melting point of -10°C and a boiling point of 242°C. In contrast, 1-Methylhydantoin-2-Imide is a white crystalline solid with a melting point of 160-162°C. It is sparingly soluble in water but soluble in organic solvents such as ethanol and acetone.

Uses

1,2-Hexanediol is commonly used as a solvent in various industries, including cosmetics, pharmaceuticals, and personal care products. It is also used as a preservative and humectant due to its antimicrobial properties and ability to retain moisture. On the other hand, 1-Methylhydantoin-2-Imide is primarily used as an intermediate in the synthesis of pharmaceutical compounds. It is also used in the production of specialty chemicals and agrochemicals.

Biological Activity

1,2-Hexanediol has been shown to exhibit antimicrobial activity against a wide range of bacteria and fungi. It is often used in skincare products for its ability to inhibit the growth of microorganisms on the skin. In contrast, 1-Methylhydantoin-2-Imide does not have significant antimicrobial properties but has been found to have anti-inflammatory and antioxidant effects. It may be used in topical formulations for its skin-soothing properties.

Safety Considerations

1,2-Hexanediol is considered to be a safe ingredient in cosmetics and personal care products when used in concentrations of up to 1%. It has low skin irritation potential and is not known to be a sensitizer. However, it is always recommended to perform a patch test before using products containing 1,2-Hexanediol. On the other hand, 1-Methylhydantoin-2-Imide has limited data available on its safety profile. It is important to follow guidelines for handling and use when working with this compound.